Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.36 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746051 | 0.78 | KMT2A (0.37) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14080627 | 0.77 | KMT2A (0.41) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14080613 | 0.77 | KMT2A (0.41) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14080566 | 0.77 | KMT2A (0.41) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL14080720 | 0.76 | CNR2 (0.41) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4744059 | 0.75 | KMT2A (0.35) | MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4743629 | 0.75 | SMN1; SMN2 (0.39) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL4746857 | 0.75 | SMN1; SMN2 (0.39) | MEN1KMT2APOLBLMNASMN1; SMN2 | |
| SCHEMBL4746052 | 0.75 | THRB (0.35) | MEN1KMT2AFABP4LMNASMN1; SMN2 | |
| SCHEMBL4746853 | 0.74 | CNR2 (0.36) | MEN1KMT2ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112251-A1 | CYCLOPROPYL-CONTAINING POLYAMINE ANALOGS AS DISEASE THERAPIES | PROGEN PHARMACEUTICALS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |