Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 4/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746051 | 0.87 | KMT2A (0.37) | MEN1KMT2ALMNASMN1; SMN2CNR2 | |
| SCHEMBL4746853 | 0.85 | CNR2 (0.36) | THRBMEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL4744059 | 0.84 | KMT2A (0.35) | MEN1KMT2ALMNASMN1; SMN2MAPT | |
| SCHEMBL4746850 | 0.76 | FABP4 (0.38) | MEN1KMT2ALMNAFABP4GAA | |
| SCHEMBL4746903 | 0.75 | KMT2A (0.42) | MEN1KMT2ALMNASMN1; SMN2FABP4 | |
| SCHEMBL5887535 | 0.75 | MAPT (0.46) | MEN1KMT2ALMNAFABP4GAA | |
| SCHEMBL5887533 | 0.75 | CA1 (0.42) | MEN1KMT2ALMNAFABP4GAA | |
| SCHEMBL4744056 | 0.75 | MEN1 (0.48) | MEN1KMT2ALMNASMN1; SMN2FABP4 | |
| SCHEMBL4747444 | 0.74 | KMT2A (0.35) | MEN1KMT2ASMN1; SMN2FABP4GAA | |
| SCHEMBL14080566 | 0.72 | KMT2A (0.41) | MEN1KMT2ALMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008112251-A1 | CYCLOPROPYL-CONTAINING POLYAMINE ANALOGS AS DISEASE THERAPIES | PROGEN PHARMACEUTICALS, INC. (US) | 2008-09-18 | — | — | WO | disclosed |