Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.40 |
| ▸ | F7 | P08709 | 1/20 | 0.40 |
| ▸ | F3 | P13726 | 1/20 | 0.40 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.40 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219782 | 0.85 | SRC (0.57) | SMN1; SMN2LMNATDP1FDPSHTT | |
| SCHEMBL10932461 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNATDP1HTTKMT2A | |
| SCHEMBL4744278 | 0.85 | SMN1; SMN2 (0.47) | SMN1; SMN2LMNATDP1HTTKMT2A | |
| SCHEMBL28096006 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2LMNATDP1FDPSHTT | |
| SCHEMBL27714398 | 0.79 | KMT2A (0.45) | SMN1; SMN2LMNATDP1FDPSHTT | |
| SCHEMBL18301043 | 0.77 | SMN1; SMN2 (0.42) | SMN1; SMN2LMNATDP1FDPSHTT | |
| SCHEMBL27647649 | 0.77 | FDPS (0.45) | SMN1; SMN2LMNATDP1FDPSHTT | |
| SCHEMBL220525 | 0.76 | SRC (0.67) | TDP1ALDH1A1SRC | |
| SCHEMBL4679260 | 0.74 | FDPS (0.44) | SMN1; SMN2LMNATDP1FDPSHTT | |
| SCHEMBL27998020 | 0.73 | LMNA (0.43) | SMN1; SMN2LMNATDP1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107148423-B | Thionucleoside derivative or salt thereof and pharmaceutical composition | 富士胶片株式会社 | 2021-07-30 | — | — | CN | disclosed |
| CN-107148423-A | Thionucleoside derivatives or its salt and medical composition | 富士胶片株式会社 | 2017-09-08 | — | — | CN | disclosed |
| WO-2008113161-A1 | PHOSPHATE PRODRUGS OF QUINAZOLINYL NITROFURANS, METHODS OF OBTAINING, AND USE OF SAME | ULYSSES PHARMACEUTICAL PRODUCTS INC. (CA) | 2008-09-25 | — | — | WO | disclosed |