Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.44 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GALR3 | O60755 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCNC | P24863 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL5177023 | 0.98 | FDPS (0.43) | FDPSBTN3A1PDE3ASMN1; SMN2KMT2A | |
| SCHEMBL5713396 | 0.84 | FDPS (0.41) | FDPSBTN3A1PDE3ASMN1; SMN2KMT2A | |
| SCHEMBL5897154 | 0.80 | SRC (0.53) | FDPSKMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL28096006 | 0.77 | SMN1; SMN2 (0.45) | FDPSSMN1; SMN2KMT2ALMNATDP1 | |
| SCHEMBL28219782 | 0.77 | SRC (0.57) | FDPSBTN3A1PDE3ASMN1; SMN2KMT2A | |
| SCHEMBL27714398 | 0.74 | KMT2A (0.45) | FDPSSMN1; SMN2KMT2ALMNATDP1 | |
| SCHEMBL4744280 | 0.74 | SMN1; SMN2 (0.45) | FDPSBTN3A1PDE3ASMN1; SMN2KMT2A | |
| SCHEMBL7165035 | 0.74 | ACHE (0.40) | FDPSKMT2ALMNAALDH1A1 | |
| SCHEMBL18301043 | 0.73 | SMN1; SMN2 (0.42) | FDPSSMN1; SMN2KMT2ALMNATDP1 | |
| SCHEMBL7164282 | 0.73 | SRC (0.36) | FDPSKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276604-B2 | Crystalline form of the sodium salt of 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid | ZENTIVA A.S. (CZ) | 2007-10-02 | — | — | US | claimed |
| EP-1556041-B1 | NEW CRYSTALLINE HYDRATES OF THE SODIUM SALT OF 3-PYRIDYL-1-HYDROXYETHYLIDENE-1,1-BISPHOSPHONIC ACID | ZENTIVA AS (CZ) | 2007-08-29 | — | — | EP | claimed |
| US-20060148762-A1 | New crystalline form of the sodium salt of 3-pyridyl-1-hydroxyehtylidene-1,1-bisphosphonic acid | ZENTIVA, A.S. (CZ) | 2006-07-06 | — | — | US | claimed |
| EP-1828214-A4 | PROCESS FOR PREPARING A PURE POLYMORPHIC FORM OF 3-PYRIDYL-1-HYDROXYETHYLIDINE-1,1-BISPHOSPHONIC ACID SODIUM SALT | JUBILANT ORGANOSYS LTD (IN) | 2008-08-13 | — | — | EP | disclosed |
| US-7276604-B2 | Crystalline form of the sodium salt of 3-pyridyl-1-hydroxyethylidene-1,1-bisphosphonic acid | ZENTIVA A.S. (CZ) | 2007-10-02 | — | — | US | disclosed |
| EP-1828214-A1 | PROCESS FOR PREPARING A PURE POLYMORPHIC FORM OF 3-PYRIDYL-1-HYDROXYETHYLIDINE-1,1-BISPHOSPHONIC ACID SODIUM SALT | Jubilant Organosys Limited (IN) | 2007-09-05 | — | — | EP | disclosed |
| EP-1556041-B1 | NEW CRYSTALLINE HYDRATES OF THE SODIUM SALT OF 3-PYRIDYL-1-HYDROXYETHYLIDENE-1,1-BISPHOSPHONIC ACID | ZENTIVA AS (CZ) | 2007-08-29 | — | — | EP | disclosed |
| US-20060148762-A1 | New crystalline form of the sodium salt of 3-pyridyl-1-hydroxyehtylidene-1,1-bisphosphonic acid | ZENTIVA, A.S. (CZ) | 2006-07-06 | — | — | US | disclosed |
| WO-2006051553-A1 | PROCESS FOR PREPARING A PURE POLYMORPHIC FORM OF 3-PYRIDYL-1-HYDROXYETHYLIDINE-1,1-BISPHOSPHONIC ACID SODIUM SALT | JUBILANT ORGANOSYS LIMITED (IN) | 2006-05-18 | — | — | WO | disclosed |
| EP-1556041-A1 | A NEW CRYSTALLINE FORM OF THE SODIUM SALT OF 3-PYRIDYL-1-HYDROXYETHYLIDENE-1,1-BISPHOSPHONIC ACID | Zentiva, A.S. (CZ) | 2005-07-27 | — | — | EP | disclosed |
| WO-2004037252-A1 | A NEW CRYSTALLINE FORM OF THE SODIUM SALT OF 3-PYRIDYL-1-HYDROXYETHYLIDENE-1,1-BISPHOSPHONIC ACID | ZENTIVA, A.S. (CZ) | 2004-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060148762-A1 | New crystalline form of the sodium salt of 3-pyridyl-1-hydroxyehtylidene-1,1-bisphosphonic acid | SLC20A1, SLC9A1, PHPT1 | FDPS 1818/4885BTN3A1 1266/4885PDE3A 3107/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.