Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3110670 | 1.00 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL3116875 | 0.89 | SMN1; SMN2 (0.43) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL3115058 | 0.84 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL8935647 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL8935651 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL6378213 | 0.78 | PPARG (0.52) | SMN1; SMN2ALDH1A1HPGDKDM4EGAA | |
| SCHEMBL6173511 | 0.77 | HTR1A (0.47) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL4748338 | 0.76 | PPARG (0.46) | SMN1; SMN2CYP1A2GAA | |
| SCHEMBL665775 | 0.76 | PPARG (0.46) | SMN1; SMN2CYP1A2GAA | |
| SCHEMBL667373 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2RAB9AALDH1A1HPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008113190-A1 | METHOD FOR THE PRODUCTION OF R-HYDROXYCARBOXYLIC ACIDS | EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (CH) | 2008-09-25 | — | — | WO | claimed |
| WO-2008113190-A1 | METHOD FOR THE PRODUCTION OF R-HYDROXYCARBOXYLIC ACIDS | EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (CH) | 2008-09-25 | — | — | WO | disclosed |