Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935651 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL6538619 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2TSHRPPARAPPARG | |
| SCHEMBL6258626 | 0.86 | PPARG (0.48) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL4744285 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL3110670 | 0.81 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL28460903 | 0.79 | CYP2D6 (0.48) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL6173511 | 0.78 | HTR1A (0.47) | SMN1; SMN2MAPK1NPC1RAB9AALDH1A1 | |
| SCHEMBL17633012 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRGAAPPARAPPARG | |
| SCHEMBL8935641 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1TSHRPPARAPPARG | |
| SCHEMBL8935639 | 0.78 | KMT2A (0.62) | SMN1; SMN2ALDH1A1TSHRPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491167-A | INHIBITORS OF CHOLESTEROL BIOSYNTHESIS | SANKYO COMPANY, LIMITED (JP) | 1996-02-13 | — | — | US | disclosed |