Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913222 | 0.91 | PDPK1 (0.32) | — | |
| SCHEMBL4742985 | 0.88 | USP1 (0.36) | USP1MDM2 | |
| SCHEMBL4744316 | 0.84 | PDE2A (0.33) | USP1METMDM2MAPTPOLB | |
| SCHEMBL3993899 | 0.80 | TP53 (0.33) | MDM2MAPTPOLB | |
| SCHEMBL4485590 | 0.80 | TP53 (0.33) | MDM2MAPTPOLB | |
| SCHEMBL3986102 | 0.80 | USP1 (0.31) | USP1 | |
| SCHEMBL4742187 | 0.79 | USP1 (0.33) | USP1 | |
| SCHEMBL4489281 | 0.79 | KCNH2 (0.34) | USP1 | |
| SCHEMBL4481630 | 0.77 | ACLY (0.31) | — | |
| SCHEMBL4492304 | 0.77 | ACLY (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107398-A2 | PYRAZINE COMPOUNDS | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |