Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 6/20 | 0.36 |
| ▸ | GNRHR | P30968 | 6/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | MDM4 | O15151 | 1/20 | 0.30 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4742187 | 0.91 | USP1 (0.33) | USP1GNRHR | |
| SCHEMBL4743760 | 0.88 | USP1 (0.32) | USP1MDM2 | |
| SCHEMBL4744316 | 0.85 | PDE2A (0.33) | USP1MDM2 | |
| SCHEMBL3986102 | 0.83 | USP1 (0.31) | USP1 | |
| SCHEMBL4913222 | 0.79 | PDPK1 (0.32) | — | |
| SCHEMBL13788905 | 0.76 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL4741763 | 0.76 | KDM4E (0.35) | USP1 | |
| SCHEMBL4485590 | 0.75 | TP53 (0.33) | MDM2 | |
| SCHEMBL3993899 | 0.75 | TP53 (0.33) | MDM2 | |
| SCHEMBL4489281 | 0.74 | KCNH2 (0.34) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008107398-A2 | PYRAZINE COMPOUNDS | BASF SE (DE) | 2008-09-12 | — | — | WO | disclosed |