Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.37 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27921993 | 0.81 | TLR8 (0.44) | LIPGMAPTL3MBTL1TLR8TLR7 | |
| SCHEMBL27997436 | 0.81 | L3MBTL1 (0.42) | MAPK1NPC1RAB9ALIPGMAPT | |
| SCHEMBL11834129 | 0.80 | MEN1 (0.51) | MAPK1NPC1GAARAB9AMAPT | |
| SCHEMBL805050 | 0.80 | ALDH1A1 (0.58) | MAPK1NPC1GAARAB9AMAPT | |
| Ammonia Solution, Strong SCHEMBL28528068 | 0.79 | MEN1 (0.50) | MAPK1NPC1GAARAB9AMAPT | |
| SCHEMBL7218454 | 0.79 | SMN1; SMN2 (0.56) | MAPK1NPC1GAARAB9AMAPT | |
| SCHEMBL6630437 | 0.79 | LMNA (0.56) | MAPK1NPC1GAARAB9AMAPT | |
| SCHEMBL11371897 | 0.79 | GAA (0.44) | MAPK1NPC1GAARAB9AMAPT | |
| SCHEMBL28015724 | 0.79 | GAA (0.44) | MAPK1NPC1GAARAB9AMAPT | |
| SCHEMBL18285791 | 0.78 | LIPG (0.49) | RAB9ALIPGMAPTL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230144106-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | SYROS PHARMACEUTICALS INC (US) | 2023-05-11 | — | — | US | disclosed |
| CN-110305136-A | A kind of pemetrexed disodium intermediate and preparation method thereof | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | disclosed |
| CN-110305137-A | A kind of pemetrexed disodium intermediate and preparation method thereof | 鲁南制药集团股份有限公司 | 2019-10-08 | — | — | CN | disclosed |
| WO-2008104875-A1 | OXAZOLIDINONES AS CHOLESTEROL ABSORPTION INHIBITORS | PFIZER PRODUCTS INC. (US) | 2008-09-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230144106-A1 | COMPOUNDS FOR THE MODULATION OF MYC ACTIVITY | MYC, MYCBP, MYCBP2 | MAPK1 847/4885NPC1 649/4885GAA 2507/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.