Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6477571 | 0.98 | MAPT (0.50) | TSHRNPC1RAB9AIDO1TAAR1 | |
| Hydrochloric Acid SCHEMBL6939134 | 0.88 | AGXT (0.69) | NPC1RAB9AIDO1AGXT | |
| SCHEMBL538293 | 0.79 | TSHR (0.57) | TSHRNPC1RAB9AIDO1AGXT | |
| Dimethylamine SCHEMBL7752537 | 0.77 | TSHR (0.79) | TSHRIDO1TAAR1MAPTAGXT | |
| Hydrochloric Acid SCHEMBL11220071 | 0.77 | TSHR (0.55) | TSHRNPC1RAB9AIDO1MAPT | |
| SCHEMBL8720456 | 0.76 | TSHR (0.48) | TSHRNPC1RAB9AIDO1MAPT | |
| SCHEMBL1983662 | 0.76 | HRAS (0.49) | TSHRNPC1RAB9AIDO1SIGMAR1 | |
| SCHEMBL13248016 | 0.76 | IDO1 (0.52) | IDO1TAAR1AGXTALDH1A1LMNA | |
| SCHEMBL18541671 | 0.76 | TSHR (0.48) | TSHRNPC1RAB9AIDO1MAPT | |
| SCHEMBL1583521 | 0.76 | LOXL2 (0.41) | TSHRMAPTKDM4ECYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1434813-A | Pyrrolidine derivatives cyclic AMP-specific phosphodiesterase inhibitors | ICOS CONP (US) | 2003-08-06 | — | — | CN | claimed |
| EP-0976760-B1 | Oligopeptides with fungicidal activity | ISAGRO SPA (IT) | 2002-12-18 | — | — | EP | claimed |
| US-6084065-A | FOR AGRICULTURAL USE | ISAGRO SPA (IT) | 2000-07-04 | — | — | US | claimed |
| EP-0652229-B1 | Oligopeptides with fungicidal activity | ISAGRO SPA (IT) | 2000-05-24 | — | — | EP | claimed |
| EP-0976760-A2 | Oligopeptides with fungicidal activity | ISAGRO S.p.A. (IT) | 2000-02-02 | — | — | EP | claimed |
| EP-0652229-A2 | Oligopeptides with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-05-10 | — | — | EP | claimed |
| US-20260069726-A1 | ZWITTERIONIC COMPOUNDS AND USES THEREOF | UNIV SASKATCHEWAN (CA) | 2026-03-12 | — | — | US | disclosed |
| US-20250064789-A1 | KETOAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | WESTVAC BIOPHARMA CO., LTD. (CN) | 2025-02-27 | — | — | US | disclosed |
| WO-2025021997-A1 | NEW MAP4K1 INHIBITORS | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) | 2025-01-30 | — | — | WO | disclosed |
| EP-4488264-A1 | KETO AMIDE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | WestVac Biopharma Co., Ltd. (CN) | 2025-01-08 | — | — | EP | disclosed |
| US-12098153-B2 | Small molecule inhibitors targeting Clostridioides difficile sporulation | UNIVERSITY OF SOUTH FLORIDA (US) | 2024-09-24 | — | — | US | disclosed |
| CN-116693447-B | Ketone amide derivative and pharmaceutical application thereof | 成都威斯克生物医药有限公司 | 2024-08-13 | — | — | CN | disclosed |
| EP-4347032-A1 | SUBSTITUTED TETRAHYDROFURAN-2-CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | Vertex Pharmaceuticals Incorporated (US) | 2024-04-10 | — | — | EP | disclosed |
| WO-1996003983-A1 | INHIBITION OF LEUKOTRIENE BIOSYNTHESIS WITH UREA DERIVATIVES | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1996-02-15 | — | — | WO | disclosed |
| WO-1995014023-A1 | SEMISYNTHETIC ANALOGS OF RAPAMYCIN (MACROLIDES) BEING IMMUNOMODULATORS | ABBOTT LABORATORIES (US) | 1995-05-26 | — | — | WO | disclosed |
| EP-0652229-A2 | Oligopeptides with fungicidal activity | ISAGRO S.p.A. (IT) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994026264-A1 | (4-ALKOXYPYRAN-4-YL) SUBSTITUTED ARYLALKYLARYL-, ARYLALKENYLARYL-, AND ARYLALKYNYLARYLUREA INHIBITORS OF 5-LIPOXYGENASE | ABBOTT LABORATORIES (US) | 1994-11-24 | — | — | WO | disclosed |
| US-4906667-A | Phenyl hydroxamic acids including a hetero-containing substituent | E. R. SQUIBB & SONS, INC. (US) | 1990-03-06 | — | — | US | disclosed |
| EP-0341694-A2 | Method for production of 3-exomethylenecepham derivatives | OTSUKA KAGAKU KABUSHIKI KAISHA (JP) | 1989-11-15 | — | — | EP | disclosed |
| EP-0082088-B1 | DERIVATIVES OF AMINO ACIDS AND THEIR THERAPEUTIC USE | Roques, Bernard (FR) | 1986-04-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260069726-A1 | ZWITTERIONIC COMPOUNDS AND USES THEREOF | CA13, SLCO2B1, SLCO2A1 | TSHR 388/4885NPC1 192/4885RAB9A 497/4885 |
| US-20250064789-A1 | KETOAMIDE DERIVATIVES AND PHARMACEUTICAL USES THEREOF | ACE2, ACE, PKD2 | TSHR 3558/4885NPC1 413/4885RAB9A 2965/4885 |
| US-12098153-B2 | Small molecule inhibitors targeting Clostridioides difficile sporulation | SPOUT1, CLPP, RPN2 | TSHR 4866/4885NPC1 863/4885RAB9A 2104/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.