Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.49 |
| ▸ | CASP7 | P55210 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GUSB | P08236 | 1/20 | 0.47 |
| ▸ | TERT | O14746 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748569 | 0.81 | LMNA (0.58) | L3MBTL1MAPTNPC1GUSBTERT | |
| SCHEMBL27890181 | 0.81 | TERT (0.69) | TERTMEN1KMT2ADOT1LMMP1 | |
| SCHEMBL3648167 | 0.79 | NPC1 (0.67) | L3MBTL1MAPTNPC1MEN1KMT2A | |
| SCHEMBL3651398 | 0.77 | MEN1 (0.57) | L3MBTL1MAPTNPC1MEN1KMT2A | |
| SCHEMBL266459 | 0.76 | CYP1A2 (0.64) | L3MBTL1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30199873 | 0.76 | CYP1A2 (0.64) | L3MBTL1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10939039 | 0.76 | KDM1A (0.70) | CASP6L3MBTL1MAPTNPC1TERT | |
| SCHEMBL3760247 | 0.74 | LMNA (0.61) | L3MBTL1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL29210682 | 0.74 | CDK2 (0.47) | L3MBTL1MAPTNPC1MEN1KMT2A | |
| SCHEMBL13962832 | 0.73 | NSD2 (0.50) | NSD2DUSP3PTPN5CASP7CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |