Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29210710 | 0.89 | ALDH1A1 (0.44) | CDK2ALDH1A1HPGDHSD17B10CYP3A4 | |
| SCHEMBL27890181 | 0.74 | TERT (0.69) | MEN1KMT2AALOX15 | |
| SCHEMBL4745308 | 0.74 | NSD2 (0.49) | CDK2HSD17B10NPSR1MEN1KMT2A | |
| SCHEMBL4748569 | 0.74 | LMNA (0.58) | CDK2NPSR1KMT2AMAPTNPY5R | |
| SCHEMBL13312384 | 0.74 | TRIM58 (0.49) | CDK2ALDH1A1NPY5RL3MBTL1KDM4E | |
| SCHEMBL12501247 | 0.72 | LMNA (0.54) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL196601 | 0.72 | GPR3 (0.64) | ALDH1A1HPGDHSD17B10NPSR1MEN1 | |
| SCHEMBL10939039 | 0.71 | KDM1A (0.70) | ALDH1A1HPGDHSD17B10CYP3A4NPSR1 | |
| SCHEMBL12501269 | 0.71 | MPO (0.58) | ALDH1A1HSD17B10MEN1KMT2AMAPT | |
| SCHEMBL17532730 | 0.71 | MAPT (0.52) | ALDH1A1HPGDHSD17B10MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324767-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-07-12 | — | — | CN | disclosed |
| CN-117736207-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-115362003-B | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2024-03-22 | — | — | CN | disclosed |
| CN-115362003-A | Diacylglycerol kinase modulating compounds | 卡尔那生物科学株式会社 | 2022-11-18 | — | — | CN | disclosed |