Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TERT | O14746 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745308 | 0.81 | NSD2 (0.49) | LMNAMAPTTERTL3MBTL1KDM1A | |
| SCHEMBL27890181 | 0.81 | TERT (0.69) | TERTDOT1LKMT2A | |
| SCHEMBL3650893 | 0.80 | DHFR (0.56) | LMNAMAPTSMN1; SMN2USP2POLB | |
| SCHEMBL3645814 | 0.77 | NPC1 (0.66) | MAPTTP53SMN1; SMN2APAF1USP2 | |
| SCHEMBL5989580 | 0.76 | KMT2A (0.56) | LMNAMAPTSMN1; SMN2APAF1USP2 | |
| SCHEMBL30824509 | 0.76 | MAPT (0.67) | LMNAMAPTL3MBTL1SMN1; SMN2USP2 | |
| SCHEMBL318704 | 0.76 | MAPT (0.67) | LMNAMAPTL3MBTL1SMN1; SMN2USP2 | |
| SCHEMBL10939039 | 0.76 | KDM1A (0.70) | LMNAMAPTTERTL3MBTL1KDM1A | |
| SCHEMBL30572382 | 0.74 | LMNA (1.00) | LMNAMAPTL3MBTL1SMN1; SMN2POLB | |
| SCHEMBL4768081 | 0.74 | LMNA (1.00) | LMNAMAPTL3MBTL1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117079-A1 | ANTIMICROBIAL COMPOUNDS BASED UPON 4-AMINOQUINOLINE | HELPERBY THERAPEUTICS LIMITED (GB) | 2008-10-02 | — | — | WO | disclosed |