Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26100054 | 0.88 | KMT2A (0.38) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL8329644 | 0.85 | NOS1 (0.33) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL28058283 | 0.85 | KMT2A (0.36) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL6932447 | 0.84 | KMT2A (0.36) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL28739490 | 0.83 | MEN1 (0.35) | MEN1GAAKMT2ANOS1NOS3 | |
| Hydrochloric Acid SCHEMBL15268739 | 0.81 | HDAC1 (0.39) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL28580983 | 0.81 | CA2 (0.47) | MEN1GAAKMT2A | |
| SCHEMBL3048518 | 0.80 | CA2 (0.46) | MEN1GAAKMT2A | |
| SCHEMBL473544 | 0.79 | NOS1 (0.33) | MEN1GAAKMT2ANOS1NOS3 | |
| SCHEMBL38661123 | 0.79 | CA2 (0.38) | MEN1GAAKMT2ANOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008110351-A2 | USE OF (R) AND (S)-2-ARYL-PROPIONIC ACID DERIVATIVES AS ANTISEPTIC AGENTS | DOMPE' PHA.R.MA S.P.A. (IT) | 2008-09-18 | — | — | WO | disclosed |