Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932447 | 0.87 | KMT2A (0.36) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL1767929 | 0.87 | KMT2A (0.36) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL4745625 | 0.85 | MEN1 (0.34) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL3809238 | 0.82 | NOS1 (0.33) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL38661123 | 0.82 | CA2 (0.38) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL473544 | 0.82 | NOS1 (0.33) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL28058283 | 0.80 | KMT2A (0.36) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL1058519 | 0.78 | CACNA2D1 (0.37) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL13312676 | 0.78 | NOS1 (0.32) | NOS1NOS3NOS2KMT2AMEN1 | |
| SCHEMBL27978913 | 0.78 | GABRR1 (0.39) | NOS1NOS3NOS2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |