Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6932447 | 0.87 | KMT2A (0.36) | KMT2AMEN1GAANOS1NOS3 | |
| SCHEMBL3622338 | 0.86 | MEN1 (0.35) | KMT2AMEN1GAANOS1NOS3 | |
| SCHEMBL6230762 | 0.86 | MEN1 (0.35) | KMT2AMEN1GAANOS1NOS3 | |
| SCHEMBL3671404 | 0.86 | MEN1 (0.35) | KMT2AMEN1GAANOS1NOS3 | |
| SCHEMBL28739490 | 0.86 | MEN1 (0.35) | KMT2AMEN1GAANOS1NOS3 | |
| SCHEMBL4745625 | 0.85 | MEN1 (0.34) | KMT2AMEN1GAANOS1NOS3 | |
| Hydrochloric Acid SCHEMBL15268739 | 0.85 | HDAC1 (0.39) | KMT2AMEN1GAANOS1NOS3 | |
| SCHEMBL28580983 | 0.85 | CA2 (0.47) | KMT2AMEN1GAACA1CA2 | |
| SCHEMBL3619677 | 0.82 | CTSK (0.33) | KMT2AMEN1GAANOS1NOS3 | |
| SCHEMBL7110422 | 0.82 | NOS1 (0.36) | KMT2AMEN1GAANOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105330657-B | The preparation method of the chloro- 2- of 5- [5- (R)-methyl-1,4- Diazesuberane -1-] benzoxazoles | 华润双鹤药业股份有限公司 | 2019-05-21 | — | — | CN | disclosed |
| CN-105330657-A | Method for preparing 5-chlorine-2[5-(R)-methyl-1,4-diazacycloheptyl-1-] benzoxazole | CHINA RESOURCES DOUBLE CRANE PHARMACEUTICAL CO LTD | 2016-02-17 | — | — | CN | disclosed |