Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RCE1 | Q9Y256 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11259360 | 0.83 | KDM4E (0.58) | RCE1TDP1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL11072398 | 0.83 | ALOX15 (0.61) | RCE1ALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL2361907 | 0.80 | CFTR (0.63) | RCE1TDP1ALDH1A1CYP3A4HSD17B10 | |
| SCHEMBL28707659 | 0.79 | KMT2A (0.51) | RCE1ALDH1A1TP53CYP1A2CYP3A4 | |
| SCHEMBL11228603 | 0.79 | TDP1 (0.50) | RCE1TDP1ALDH1A1TP53CYP1A2 | |
| SCHEMBL19102660 | 0.78 | TSHR (0.50) | RCE1TDP1ALDH1A1TP53KDM4E | |
| SCHEMBL7657652 | 0.76 | POLB (0.76) | ALDH1A1CYP3A4CYP2C9KDM4EKMT2A | |
| SCHEMBL1663456 | 0.75 | HCAR3 (0.55) | TDP1ALDH1A1TP53CYP3A4HPGD | |
| SCHEMBL29665053 | 0.75 | MAPT (0.52) | RCE1TDP1ALDH1A1TP53CYP1A2 | |
| SCHEMBL28359204 | 0.75 | KMT2A (0.77) | RCE1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008121570-A1 | COMPOUNDS AND METHODS FOR MODULATING G PROTEIN-COUPLED RECEPTORS | IRM LLC (BM) | 2008-10-09 | — | — | WO | disclosed |