Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 3/20 | 0.54 |
| ▸ | LDHA | P00338 | 1/20 | 0.52 |
| ▸ | LDHB | P07195 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745633 | 0.83 | RCE1 (0.64) | KDM4ETDP1ALDH1A1HDAC1RCE1 | |
| SCHEMBL10388717 | 0.81 | HDAC3 (0.59) | KDM4EALDH1A1HDAC3HDAC1HDAC2 | |
| SCHEMBL6376702 | 0.80 | GAA (0.73) | KDM4ETDP1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL5604987 | 0.80 | GAA (0.73) | KDM4ETDP1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL1884341 | 0.80 | GAA (0.73) | KDM4ETDP1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL11256349 | 0.80 | SMN1; SMN2 (0.59) | KDM4ETDP1ALDH1A1GAANPC1 | |
| SCHEMBL27470408 | 0.79 | ALDH1A1 (0.62) | KDM4ETDP1ALDH1A1HDAC3HDAC1 | |
| SCHEMBL31521467 | 0.79 | HTR6 (0.48) | KDM4ETDP1ALDH1A1RCE1NPC1 | |
| SCHEMBL31521468 | 0.79 | HTR6 (0.48) | KDM4ETDP1ALDH1A1RCE1NPC1 | |
| SCHEMBL1663456 | 0.79 | HCAR3 (0.55) | KDM4ETDP1ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4350822-A | Antilipidemicpara-[aryl(alkyl or alkenyl)amino]benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1982-09-21 | — | — | US | disclosed |
| US-4246275-A | Antilipidemic para-[thienyl and furyl (alkyl or alkenyl)amino]-benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1981-01-20 | — | — | US | disclosed |
| US-4185115-A | Antilipidemic para-[aryl(alkyl or alkenyl)amino]-benzoic acid derivatives | AMERICAN CYANAMID COMPANY (US) | 1980-01-22 | — | — | US | disclosed |