Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | RECQL | P46063 | 1/20 | 0.71 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 4/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750190 | 0.93 | CYP2D6 (0.74) | CYP2D6CYP2C19CYP1A2RECQLL3MBTL1 | |
| SCHEMBL15092821 | 0.92 | CYP2D6 (0.76) | CYP2D6CYP2C19CYP1A2RECQLL3MBTL1 | |
| SCHEMBL4749239 | 0.88 | CYP2D6 (0.68) | CYP2D6CYP2C19CYP1A2RECQLL3MBTL1 | |
| SCHEMBL4748598 | 0.87 | CYP1A2 (0.67) | CYP2D6CYP2C19CYP1A2RECQLL3MBTL1 | |
| SCHEMBL4749180 | 0.85 | LMNA (0.71) | CYP2C19KMT2AMEN1ALDH1A1CYP2C9 | |
| SCHEMBL3260049 | 0.85 | CYP2D6 (0.95) | CYP2D6CYP2C19CYP1A2RECQLKMT2A | |
| SCHEMBL3207575 | 0.84 | CYP2D6 (0.97) | CYP2D6CYP2C19CYP1A2RECQLKMT2A | |
| SCHEMBL32664264 | 0.83 | L3MBTL1 (0.82) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL26496469 | 0.83 | L3MBTL1 (0.82) | L3MBTL1KMT2AMEN1NPC1RAB9A | |
| SCHEMBL4749787 | 0.83 | ALOX5 (0.57) | CYP2D6CYP2C19CYP1A2RECQLL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |