Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TERT | O14746 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4749308 | 0.95 | LMNA (0.62) | ALOX5KMT2ALMNAALDH1A1POLB | |
| SCHEMBL4748961 | 0.88 | CYP2D6 (0.65) | ALOX5LMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14041580 | 0.85 | POLB (0.63) | KMT2ALMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4750027 | 0.84 | KMT2A (0.65) | KMT2ALMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4748608 | 0.83 | LMNA (0.60) | KMT2ALMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL14041496 | 0.83 | KMT2A (0.60) | KMT2ALMNAALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4745790 | 0.83 | ALOX5 (0.64) | ALOX5KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL4746006 | 0.83 | CYP2D6 (0.71) | KMT2ALMNAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL4749180 | 0.80 | LMNA (0.71) | KMT2ALMNAALDH1A1POLBMEN1 | |
| SCHEMBL8227510 | 0.79 | ALDH1A1 (0.83) | KMT2ALMNAALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |