Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 10/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | DDX3X | O00571 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750231 | 0.96 | TERT (0.69) | TERTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL4750076 | 0.95 | TERT (0.72) | TERTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL13591902 | 0.94 | TERT (0.71) | TERTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL4750226 | 0.89 | KMT2A (0.71) | TERTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL4749305 | 0.87 | TERT (0.63) | TERTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL13591868 | 0.85 | L3MBTL1 (0.73) | TERTSMN1; SMN2ALDH1A1LMNAMAPT | |
| SCHEMBL13591876 | 0.84 | TSHR (0.73) | TERTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL14608018 | 0.82 | SMN1; SMN2 (0.71) | TERTSMN1; SMN2ALDH1A1POLBLMNA | |
| SCHEMBL3221943 | 0.81 | POLB (0.78) | TERTSMN1; SMN2ALDH1A1POLBMAPK1 | |
| SCHEMBL4749239 | 0.81 | CYP2D6 (0.68) | SMN1; SMN2ALDH1A1POLBLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |