Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.71 |
| ▸ | POLB | P06746 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TERT | O14746 | 4/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746440 | 0.89 | TERT (0.67) | KMT2AALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL4748864 | 0.88 | ALDH1A1 (0.68) | KMT2AALDH1A1POLBLMNAMEN1 | |
| SCHEMBL4750231 | 0.88 | TERT (0.69) | KMT2AALDH1A1POLBLMNAMEN1 | |
| SCHEMBL3012622 | 0.84 | ALDH1A1 (1.00) | KMT2AALDH1A1POLBLMNANPC1 | |
| SCHEMBL4750027 | 0.84 | KMT2A (0.65) | KMT2AALDH1A1POLBLMNANPC1 | |
| SCHEMBL4750076 | 0.83 | TERT (0.72) | KMT2AALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL4748608 | 0.83 | LMNA (0.60) | KMT2AALDH1A1POLBLMNACYP2C19 | |
| SCHEMBL14041580 | 0.82 | POLB (0.63) | KMT2AALDH1A1POLBLMNANPC1 | |
| SCHEMBL13591902 | 0.82 | TERT (0.71) | KMT2AALDH1A1POLBLMNASMN1; SMN2 | |
| SCHEMBL14041588 | 0.82 | ALDH1A1 (0.62) | KMT2AALDH1A1POLBLMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |