Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 8/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | DDX3X | O00571 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746440 | 0.96 | TERT (0.67) | TERTSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL4750076 | 0.94 | TERT (0.72) | TERTSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL13591902 | 0.92 | TERT (0.71) | TERTSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL4750226 | 0.88 | KMT2A (0.71) | TERTSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL4749305 | 0.86 | TERT (0.63) | TERTSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL14041779 | 0.84 | ALDH1A1 (0.66) | TERTSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL13591868 | 0.84 | L3MBTL1 (0.73) | TERTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4750130 | 0.83 | ALDH1A1 (0.70) | TERTALDH1A1KMT2APOLBLMNA | |
| SCHEMBL13591876 | 0.82 | TSHR (0.73) | TERTSMN1; SMN2ALDH1A1KMT2APOLB | |
| SCHEMBL14355616 | 0.82 | TERT (1.00) | TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |