Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28995655 | 0.90 | MAPT (0.44) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL14413848 | 0.86 | MAPT (0.40) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL24266297 | 0.75 | MAPT (0.42) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL34472545 | 0.75 | HCAR3 (0.40) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL4749323 | 0.75 | CCNA2 (0.41) | CCNA2CDK2HTR6CTSLCTSB | |
| SCHEMBL18202585 | 0.73 | HCAR3 (0.43) | MAPTCYP1A2CYP2C9CYP2C19CDK2 | |
| SCHEMBL8241703 | 0.73 | MAPT (0.48) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL4964715 | 0.73 | MAPT (0.48) | MAPTCYP1A2CYP2C9CYP2C19HTT | |
| SCHEMBL14042956 | 0.72 | ALDH1A1 (0.50) | MAPTHTTLMNAALDH1A1KCNH2 | |
| SCHEMBL27644625 | 0.72 | KDM1A (0.40) | CCNA2CDK2HTR6KCNH2CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |