Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648591 | 0.84 | MEN1 (0.51) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL12379255 | 0.83 | KDM4E (0.46) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL4744350 | 0.76 | MEN1 (0.43) | ALDH1A1KMT2AMEN1GAASMN1; SMN2 | |
| SCHEMBL2290004 | 0.72 | SLC6A3 (0.56) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL24074531 | 0.70 | KDM4E (0.61) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL29057021 | 0.69 | KDM4E (0.43) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL14330483 | 0.69 | ELANE (0.49) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL30070812 | 0.69 | ELANE (0.49) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL12417943 | 0.69 | TSHR (0.62) | ALDH1A1TSHRKDM4EKMT2AMEN1 | |
| SCHEMBL3869825 | 0.68 | GRM6 (0.33) | ALDH1A1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |