Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SGMS2 | Q8NHU3 | 4/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PPIA | P62937 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744350 | 0.91 | MEN1 (0.43) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL4747442 | 0.84 | ALDH1A1 (0.37) | MEN1KMT2ASMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL4415350 | 0.71 | HTT (0.75) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL2844752 | 0.70 | HTT (0.64) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL1006768 | 0.70 | HTT (0.64) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL9574717 | 0.70 | HTT (0.73) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL978857 | 0.70 | HTT (0.64) | MEN1KMT2ASMN1; SMN2NPSR1HTT | |
| SCHEMBL29433417 | 0.69 | SGMS2 (0.66) | KMT2AHTTALDH1A1LMNASGMS2 | |
| SCHEMBL112903 | 0.69 | SGMS2 (0.66) | KMT2AHTTALDH1A1LMNASGMS2 | |
| SCHEMBL9696207 | 0.69 | SGMS2 (0.66) | MEN1KMT2AHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960518-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007067559-A2 | ANTIBACTERIAL AGENTS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2007-06-14 | — | — | WO | disclosed |