Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM6 | O15303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GLA | P06280 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | CFTR | P13569 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL976497 | 0.72 | MMP2 (0.47) | GRM6ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL9269293 | 0.72 | GRM6 (0.38) | GRM6ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL2730411 | 0.72 | GRM6 (0.49) | GRM6ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL27651123 | 0.71 | GRM6 (0.42) | GRM6ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL6995362 | 0.71 | ALDH1A1 (0.53) | GRM6ALDH1A1KDM4EHPGDGLA | |
| SCHEMBL9269299 | 0.71 | SMN1; SMN2 (0.36) | GRM6ALDH1A1KDM4EHSD17B10CFTR | |
| SCHEMBL3869823 | 0.70 | HDAC3 (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL4747442 | 0.68 | ALDH1A1 (0.37) | ALDH1A1KDM4EGAA | |
| SCHEMBL25063427 | 0.68 | ADRA1A (0.41) | ALDH1A1KDM4EHPGDGLAGAA | |
| SCHEMBL6577373 | 0.67 | GRM6 (0.43) | GRM6ALDH1A1KDM4EHPGDGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7538182-B2 | Polypeptide and protein derivatives and process for their preparation | AMYLIN PHARMACEUTICALS, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| US-20070037967-A1 | conjugated by bridging molecules to proteins or polypeptides, reporter groups or cytotoxic agents; cancer | AMYLIN PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | disclosed |
| US-7129327-B2 | Polypeptide and protein derivatives and process for their preparation | AMYLIN PHARMACEUTICALS, INC. (US) | 2006-10-31 | — | — | US | disclosed |
| US-20040081660-A1 | Polypeptide and protein derivatives and process for their preparation | AMYLIN PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| US-6673347-B1 | CONJUGATED TO POLYMER VIA SCHIFF BASE, HYDRAZONE, OXIME, OR AZOMETHINE COMPOUND; DIAGNOSING TUMORS AND METASTASIS | GRYPHON THERAPEUTICS | 2004-01-06 | — | — | US | disclosed |
| EP-0243929-B1 | Polypeptide and protein derivatives and process for their preparation | OFFORD ROBIN EWART (CH) | 1995-09-27 | — | — | EP | disclosed |
| EP-0243929-A2 | Polypeptide and protein derivatives and process for their preparation | Offord, Robin Ewart (CH) | 1987-11-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037967-A1 | conjugated by bridging molecules to proteins or polypeptides, reporter groups or cytotoxic agents; cancer | HDGFL3, HCCS, HDGF | GRM6 4628/4885ALDH1A1 3182/4885KDM4E 4779/4885 |
| US-20040081660-A1 | Polypeptide and protein derivatives and process for their preparation | INSRR, GIPR, HM13 | GRM6 3270/4885ALDH1A1 4808/4885KDM4E 4630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.