Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | STS | P08842 | 7/20 | 0.49 |
| ▸ | AQP1 | P29972 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11381561 | 0.89 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL2876098 | 0.85 | KDM4E (0.80) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL2875469 | 0.83 | HPGD (0.52) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL11842239 | 0.82 | KDM4E (0.75) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL11787813 | 0.82 | KDM4E (0.78) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL11792220 | 0.81 | KDM4E (0.77) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL574020 | 0.80 | HSD17B10 (0.64) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL11849523 | 0.80 | CNR2 (0.46) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| SCHEMBL2741972 | 0.80 | ALDH1A1 (0.48) | ALDH1A1HSD17B10TSHRLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL4751053 | 0.79 | HSD17B10 (0.62) | ALDH1A1HSD17B10TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131219-A1 | SUBSTITUTED ANTHRANILIC ACIDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| WO-2008131219-A1 | SUBSTITUTED ANTHRANILIC ACIDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-30 | — | — | WO | disclosed |
| US-20080262086-A1 | SUBSTITUTED ANTHRANILIC ACIDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080262086-A1 | SUBSTITUTED ANTHRANILIC ACIDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| US-20080262086-A1 | SUBSTITUTED ANTHRANILIC ACIDS | AUSPEX PHARMACEUTICALS, INC. (US) | 2008-10-23 | — | — | US | disclosed |
| US-3963777-A | MUSCLE RELAXANTS, SEDATIVES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080262086-A1 | SUBSTITUTED ANTHRANILIC ACIDS | GLS, ASNS, REN | ALDH1A1 1760/4885HSD17B10 429/4885TSHR 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.