Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055477 | 0.66 | CES1 (0.41) | — | |
| SCHEMBL12484452 | 0.65 | TSHR (0.33) | — | |
| SCHEMBL1338419 | 0.65 | TRPV4 (0.33) | — | |
| SCHEMBL31397047 | 0.65 | TRPV4 (0.39) | CA1CA2CA4 | |
| SCHEMBL21773331 | 0.65 | CA1 (0.48) | CA1CA2CA4 | |
| SCHEMBL2264723 | 0.64 | CA2 (0.38) | CA1CA2 | |
| SCHEMBL21999840 | 0.63 | CA1 (0.48) | CA1CA2CA4 | |
| SCHEMBL21872141 | 0.62 | HSD11B1 (0.52) | CA1CA2 | |
| SCHEMBL29469794 | 0.62 | HSD11B1 (0.52) | CA1CA2 | |
| SCHEMBL30727415 | 0.61 | BCL2L1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008129276-A1 | DISULFONAMIDES USEFUL IN THE TREATMENT OF INFLAMMATION | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-30 | — | — | WO | disclosed |