Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 7/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | SIRT6 | Q8N6T7 | 7/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744340 | 0.88 | ALDH1A1 (0.61) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL19350802 | 0.84 | MAPT (0.69) | HTR6MAPTMAPK1MEN1KMT2A | |
| SCHEMBL31237089 | 0.84 | MAPT (0.56) | HTR6MAPTMAPK1MEN1KMT2A | |
| SCHEMBL1845227 | 0.83 | MAPT (0.70) | HTR6MAPTMAPK1MEN1KMT2A | |
| SCHEMBL31237044 | 0.82 | L3MBTL1 (0.47) | HTR6MAPTMAPK1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL1845124 | 0.82 | MAPT (0.69) | HTR6MAPTMAPK1MEN1KMT2A | |
| SCHEMBL31237055 | 0.81 | MAPT (0.59) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL4930639 | 0.80 | L3MBTL1 (0.62) | MAPTMAPK1MEN1KMT2ATDP1 | |
| SCHEMBL2324309 | 0.78 | L3MBTL1 (0.56) | MAPTMAPK1TDP1L3MBTL1ALDH1A1 | |
| SCHEMBL3949905 | 0.78 | LMNA (0.75) | HTR6MAPTMAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |