Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 12/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747675 | 0.88 | HTR6 (0.61) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL31237089 | 0.86 | MAPT (0.56) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL31144796 | 0.85 | MAPT (0.60) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL31237016 | 0.82 | LMNA (0.47) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL4930639 | 0.82 | L3MBTL1 (0.62) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL1842394 | 0.82 | MAPT (0.67) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL31237099 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL31237038 | 0.80 | MAPT (0.54) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL31237055 | 0.79 | MAPT (0.59) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL4850812 | 0.78 | MAPT (0.56) | ALDH1A1MAPTMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |