Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13937352 | 0.82 | MEN1 (0.40) | ALDH1A1MEN1KMT2ANPC1POLB | |
| SCHEMBL645528 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2ANPC1POLB | |
| SCHEMBL3311939 | 0.73 | KMT2A (0.41) | ALDH1A1MEN1KMT2ANPC1POLB | |
| SCHEMBL10722207 | 0.72 | PKM (0.47) | ALDH1A1MEN1KMT2ANPC1POLB | |
| SCHEMBL29535143 | 0.70 | RARA (0.51) | ALDH1A1MEN1KMT2AHTTCNR2 | |
| SCHEMBL178217 | 0.70 | RARA (0.51) | ALDH1A1MEN1KMT2AHTTCNR2 | |
| SCHEMBL819782 | 0.69 | RARA (0.50) | ALDH1A1MEN1KMT2AHTTCNR2 | |
| SCHEMBL28281248 | 0.69 | HDAC11 (0.53) | ALDH1A1MEN1KMT2AHTTCNR2 | |
| SCHEMBL30076502 | 0.68 | HDAC11 (0.40) | ALDH1A1MEN1KMT2AHTTCNR2 | |
| SCHEMBL3309247 | 0.67 | HDAC11 (0.43) | ALDH1A1MEN1KMT2AHTTCNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008126104-A2 | NOVEL PROCESS FOR PREPARATION OF ADAPALENE | INDOCO REMEDIES LIMITED (IN) | 2008-10-23 | — | — | WO | disclosed |