Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL2354924 | 0.98 | ALDH1A1 (0.50) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL14524633 | 0.98 | ALDH1A1 (0.50) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL3299959 | 0.96 | KDM4E (0.55) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL19801508 | 0.92 | ALDH1A1 (0.46) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL22416459 | 0.92 | ALDH1A1 (0.46) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL2614641 | 0.92 | HRH3 (0.57) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL10922490 | 0.90 | ALDH1A1 (0.55) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL19801513 | 0.89 | KDM4E (0.50) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL19801507 | 0.89 | KDM4E (0.50) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 | |
| SCHEMBL21348421 | 0.88 | MAPK1 (0.54) | ALDH1A1MAPK1CYP1A2CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411435-A1 | POLYURETHANE GELS AND METHOD FOR THE PRODUCTION THEREOF | GT Elektrotechnische Produkte GmbH (DE) | 2012-02-01 | — | — | EP | claimed |
| WO-2010108541-A1 | POLYURETHANE GELS AND METHOD FOR THE PRODUCTION THEREOF | GT ELEKTROTECHNISCHE PRODUKTE GMBH (DE) | 2010-09-30 | — | — | WO | claimed |
| EP-1525235-A1 | MICROSTRUCTURE CHAIN TRANSFER AGENTS FOR ANIONIC POLYMERIZATION | Hellermann, Walter (DE) | 2005-04-27 | — | — | EP | claimed |
| WO-2004014966-A1 | MICROSTRUCTURE CHAIN TRANSFER AGENTS FOR ANIONIC POLYMERIZATION | HELLERMANN WALTER (DE) | 2004-02-19 | — | — | WO | claimed |
| EP-4281439-A1 | SMALL MOLECULE REGULATORS OF ALVEOLAR TYPE 2 CELL PROLIFERATION FOR THE TREATMENT OF PULMONARY DISEASES | The Scripps Research Institute (US) | 2023-11-29 | — | — | EP | disclosed |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | InventisBio Co., Ltd. (CN) | 2023-11-09 | — | — | US | disclosed |
| EP-4272825-A2 | MTORC MODULATORS AND USES THEREOF | Aeovian Pharmaceuticals, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
| WO-2023109912-A1 | 3, 4-DIHYDROISOQUINOLIN-1 (2H) -ONES DERIVATIVES AS STING ANTAGONISTS AND THE USE THEREOF | BEIGENE, LTD. (KY) | 2023-06-22 | — | — | WO | disclosed |
| US-20230142839-A1 | N4-phenyl-quinazoline-4 -amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases | ARRAY BIOPHARMA INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-11524940-B1 | Inhibitors of cysteine proteases and methods of use thereof | Pardes Biosciences, Inc. (US) | 2022-12-13 | — | — | US | disclosed |
| US-20220389017-A1 | NOVEL PURINE DERIVATIVE, INTERMEDIATE AND APPLICATION THEREOF IN PREPARING ANTICANCER MEDICINE | SUZHOU RAYMON PHARMACEUTICALS COMPANY, LTD. (CN) | 2022-12-08 | — | — | US | disclosed |
| US-4077859-A | Polyunsaturated halogenated monomers for use in ultraviolet coating systems | CELANESE CORPORATION (US) | 1978-03-07 | — | — | US | disclosed |
| US-4042476-A | TITANIUM DIOXIDE-ACRYLIC POLYMER EMULSION | CELANESE CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-4035321-A | Preparation of ultraviolet curable acrylated polymers | CELANESE CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |
| US-4016334-A | Method of applying high adhesion ultraviolet curable coatings and coated articles | CELANESE CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |
| US-4008293-A | ACRYLIC COPOLYMER, AMINOPLAST, BINDER | PPG INDUSTRIES, INC. (US) | 1977-02-15 | — | — | US | disclosed |
| US-3992276-A | Unsaturated polyesters for ultraviolet curable coatings | CELANESE CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3992275-A | Low gloss ultraviolet curable coatings utilizing α,α,α-trichlorotoluene as a photoinitiator | CELANESE CORPORATION (US) | 1976-11-16 | — | — | US | disclosed |
| US-3943153-A | BACTERICIDES | MERCK & CO., INC. (US) | 1976-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220389017-A1 | NOVEL PURINE DERIVATIVE, INTERMEDIATE AND APPLICATION THEREOF IN PREPARING ANTICANCER MEDICINE | PNP, ENTPD5, NTPCR | ALDH1A1 999/4885MAPK1 152/4885CYP1A2 2642/4885 |
| US-20230142839-A1 | N4-phenyl-quinazoline-4 -amine derivatives and related compounds as ErbB type I receptor tyrosine kinase inhibitors for the treatment of hyperproliferative diseases | ERBB4, ERBB2, ERBB3 | ALDH1A1 2816/4885MAPK1 182/4885CYP1A2 2406/4885 |
| US-20230357233-A1 | HETEROARYL COMPOUNDS, PREPARATION METHODS AND USES THEREOF | KRAS, NRAS, HRAS | ALDH1A1 1158/4885MAPK1 435/4885CYP1A2 1409/4885 |
| US-11524940-B1 | Inhibitors of cysteine proteases and methods of use thereof | CTRL, CTSV, CTSL | ALDH1A1 2252/4885MAPK1 4455/4885CYP1A2 2410/4885 |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | ALDH1A1 1863/4885MAPK1 4249/4885CYP1A2 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.