SCHEMBL2614641

SCHEMBL2614641

CCOCCCN1CCOCC1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 4/20 0.57
ALDH1A1 P00352 3/20 0.57
MAPK1 P28482 2/20 0.57
CYP1A2 P05177 1/20 0.57
CHRM2 P08172 1/20 0.57
CHRM1 P11229 1/20 0.57
HTR2A P28223 1/20 0.57
SCN1A P35498 1/20 0.57
HTR2B P41595 1/20 0.57
KCNH2 Q12809 1/20 0.57
SCN2A Q99250 1/20 0.57
SIGMAR1 Q99720 1/20 0.57
SCN3A Q9NY46 1/20 0.57
USP2 O75604 1/20 0.56
LMNA P02545 1/20 0.56
KEAP1 Q14145 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
KDM4E B2RXH2 4/20 0.49
HTT P42858 2/20 0.49
CYP2D6 P10635 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21348421 0.96 MAPK1 (0.54) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL10922490 0.94 ALDH1A1 (0.55) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL474810 0.92 ALDH1A1 (0.51) HRH3ALDH1A1MAPK1CYP1A2CHRM2
Bromide SCHEMBL2354924 0.90 ALDH1A1 (0.50) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL14524633 0.90 ALDH1A1 (0.50) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL3299959 0.88 KDM4E (0.55) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL5293921 0.87 KEAP1 (0.58) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL10928264 0.86 ALDH1A1 (0.60) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL20333202 0.86 HTT (0.52) HRH3ALDH1A1MAPK1CYP1A2CHRM2
SCHEMBL11569854 0.85

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7468399-B2 Antifouling condensation curing organopolysiloxane composition and underwater structure SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-23 US claimed
EP-1634928-B1 Antifouling condensation curing organopolysiloxane composition and underwater structure SHINETSU CHEMICAL CO (JP) 2007-10-31 EP claimed
EP-3892701-B1 UV CURABLE SILICONE ADHESIVE COMPOSITION AND CURED PRODUCT THEREOF SHINETSU CHEMICAL CO (JP) 2026-03-04 EP disclosed
US-20250287559-A1 MICROSTRUCTURE-TRANSFER APPARATUS, STAMP HEAD UNIT, STAMP COMPONENT FOR TRANSFERRING MICROSTRUCTURE, AND METHOD FOR TRANSFERRING MICROSTRUCTURE-INTEGRATED COMPONENT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-09-11 US disclosed
US-12342467-B2 Microstructure-transfer apparatus, stamp head unit, stamp component for transferring microstructure, and method for transferring microstructure-integrated component SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-24 US disclosed
US-12168745-B2 Ultraviolet ray curable silicone adhesive composition and cured product thereof SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-12-17 US disclosed
CN-115038767-B Addition-curable silicone pressure-sensitive adhesive composition and cured product thereof 信越化学工业株式会社 2024-07-26 CN disclosed
CN-113396485-B Microstructure transferring device, template head unit, template member for microstructure transferring, and method for transferring microstructure integrated member 信越化学工业株式会社 2024-07-26 CN disclosed
CN-118352439-A Microstructure transferring device, template head unit, template member for microstructure transferring, and method for transferring microstructure integrated member 信越化学工业株式会社 2024-07-16 CN disclosed
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF KUMQUAT BIOSCIENCES INC. 2024-07-11 US disclosed
EP-3885420-B1 ULTRAVIOLET RAY CURABLE SILICONE ADHESIVE COMPOSITION AND CURED PRODUCT THEREOF SHINETSU CHEMICAL CO (JP) 2023-11-29 EP disclosed
US-7468399-B2 Antifouling condensation curing organopolysiloxane composition and underwater structure SHIN-ETSU CHEMICAL CO., LTD. (JP) 2008-12-23 US disclosed
US-20080293712-A1 Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof WYETH (US) 2008-11-27 US disclosed
US-7326790-B2 Diphenylisoxazole compounds and hydro isomers thereof RIGEL PHARMACEUTICALS, INC. (US) 2008-02-05 US disclosed
US-20080004273-A1 Inhibitors of protein tyrosine kinase activity METHYLGENE, INC. (CA) 2008-01-03 US disclosed
EP-1634928-B1 Antifouling condensation curing organopolysiloxane composition and underwater structure SHINETSU CHEMICAL CO (JP) 2007-10-31 EP disclosed
US-7220745-B2 Heterocyclic compounds useful to treat HCV RIGEL PHARMACEUTICALS (US) 2007-05-22 US disclosed
US-20060058452-A1 Antifouling condensation curing organopolysiloxane composition and underwater structure SHIN-ETSU CHEMICAL CO., LTD. 2006-03-16 US disclosed
EP-1634928-A1 Antifouling condensation curing organopolysiloxane composition and underwater structure SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-03-15 EP disclosed
WO-2004052847-A2 TRICYCLIC STEROID HORMONE NUCLEAR RECEPTOR MODULATORS ELI LILLY AND COMPANY (US) 2004-06-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240226113-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TP53, HRAS, KRAS HRH3 2868/4885ALDH1A1 2917/4885MAPK1 416/4885
US-20080004273-A1 Inhibitors of protein tyrosine kinase activity HGF, ERBB2, MET HRH3 2228/4885ALDH1A1 3139/4885MAPK1 168/4885
US-20080293712-A1 Benzo[C][2,7]Naphtyridine Derivatives, Methods of Making Thereof and Methods of Use Thereof PDPK1, PDK2, PDK3 HRH3 949/4885ALDH1A1 2573/4885MAPK1 168/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.