Sugi Predict

Sugi Predict / Compounds / SCHEMBL4748141

SCHEMBL4748141

SCHEMBL4748141

CC(C)CC[C@@H](O)CC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SLC22A6 Q4U2R8 1/20 0.57
▸ GPR84 Q9NQS5 4/20 0.54
▸ MAPT P10636 1/20 0.48
▸ GABRR1 P24046 2/20 0.48
▸ LMNA P02545 1/20 0.48
▸ MMP12 P39900 3/20 0.40
▸ MMP13 P45452 3/20 0.40
▸ CACNA2D1 P54289 2/20 0.40
▸ CACNB3 P54284 1/20 0.40
▸ CACNA1C Q13936 1/20 0.40
▸ MMP2 P08253 1/20 0.40
▸ MMP9 P14780 1/20 0.40
▸ MMP14 P50281 1/20 0.40
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ PGR P06401 1/20 0.40
▸ ADRA1A P35348 1/20 0.40
▸ HTR2B P41595 1/20 0.40
▸ CACNA2D2 Q9NY47 1/20 0.40
▸ SLC1A3 P43003 1/20 0.38
▸ SLC1A2 P43004 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL665350 1.00 SLC22A6 (0.57) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL12327762 0.89 SLC22A6 (0.50) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL13800587 0.89 SLC22A6 (0.50) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL12722973 0.89 SLC22A6 (0.50) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL26138089 0.87 SLC22A6 (0.75) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL4749028 0.86 GPR84 (0.61) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL668070 0.86 GPR84 (0.67) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL667381 0.86 GPR84 (0.61) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL4747834 0.86 GPR84 (0.67) SLC22A6GPR84MAPTGABRR1LMNA
SCHEMBL16600523 0.85 SLC22A6 (0.57) SLC22A6GPR84MAPTGABRR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008113190-A1 METHOD FOR THE PRODUCTION OF R-HYDROXYCARBOXYLIC ACIDS EMPA EIDGENÖSSISCHE MATERIALPRÜFUNGS- UND FORSCHUNGSANSTALT (CH) 2008-09-25 — — WO claimed
EP-1036190-B1 A METHOD FOR PRODUCING HYDROXYCARBOXYLIC ACIDS BY AUTO-DEGRADATION OF POLYHYDROXYALKANOATES CHIROBIO INC (KR) 2005-05-11 — — EP claimed
US-6472188-B1 SYNTHESIZING AND ACCUMULATING POLYHYDROXYALKANOATES (PHA) IN A CELL OF A MICROORGANISM BY CULTURING THE MICROORGANISM HAVING POLYHYDROXYALKANOATE DEPOLYMERASE ACTIVITY, COLLECTING CULTURED POLYMER, SUBJECTING TO MICROBIAL ENZYME DEGRADATION CHIROBIO INC. (KR) 2002-10-29 — — US claimed
CN-114874293-B Cyclic polypeptide compound and preparation method and application thereof 中国医学科学院医药生物技术研究所 2025-05-23 — — CN disclosed
US-20230303494-A1 BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF ACADEMY OF MILITARY MEDICAL SCIENCES (CN) 2023-09-28 — — US disclosed
CN-114874293-A Cyclic polypeptide compounds and preparation method and application thereof 中国医学科学院医药生物技术研究所 2022-08-09 — — CN disclosed
EP-2088152-A1 N'-{N-[3-OXO-LUPEN-28-OYL]-9-AMINONONANOYL}-3-AMINO-3-PHENYLPROPEONIC ACID AND THE PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF, A METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A MEDICINAL AGENT Institut Neftekhimii I Kataliza Rossiiskoi Akademii Nauk (RU) 2009-08-12 — — EP disclosed
EP-1176135-B1 Process for producing optically active alcohol TAKASAGO PERFUMERY CO LTD (JP) 2005-06-15 — — EP disclosed
EP-1036190-B1 A METHOD FOR PRODUCING HYDROXYCARBOXYLIC ACIDS BY AUTO-DEGRADATION OF POLYHYDROXYALKANOATES CHIROBIO INC (KR) 2005-05-11 — — EP disclosed
US-6492545-B2 Process for producing optically active alcohol TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-12-10 — — US disclosed
US-6472188-B1 SYNTHESIZING AND ACCUMULATING POLYHYDROXYALKANOATES (PHA) IN A CELL OF A MICROORGANISM BY CULTURING THE MICROORGANISM HAVING POLYHYDROXYALKANOATE DEPOLYMERASE ACTIVITY, COLLECTING CULTURED POLYMER, SUBJECTING TO MICROBIAL ENZYME DEGRADATION CHIROBIO INC. (KR) 2002-10-29 — — US disclosed
US-20020035283-A1 Process for producing optically active alcohol TAKASAGO INTERNATIONAL CORPORATION 2002-03-21 — — US disclosed
EP-1176135-A1 Process for producing optically active alcohol Takasago International Corporation (JP) 2002-01-30 — — EP disclosed
EP-1036190-A1 A METHOD FOR PRODUCING HYDROXYCARBOXYLIC ACIDS BY AUTO-DEGRADATION OF POLYHYDROXYALKANOATES ChiroBio Inc. (KR) 2000-09-20 — — EP disclosed
WO-1999029889-A1 A METHOD FOR PRODUCING HYDROXYCARBOXYLIC ACIDS BY AUTO-DEGRADATION OF POLYHYDROXYALKANOATES LG CHEMICAL LTD. (KR) 1999-06-17 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230303494-A1 BENZYLAMINE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF CD274, PDCD1, PDCD1LG2 SLC22A6 1268/4885GPR84 2674/4885MAPT 2862/4885
US-20020035283-A1 Process for producing optically active alcohol ADH1A, ADH5, ADH1C SLC22A6 4482/4885GPR84 868/4885MAPT 3700/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.