Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.32 |
| ▸ | RHOA | P61586 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CTSA | P10619 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4855914 | 0.80 | GPR119 (0.33) | GPR119CNR1TRPM4 | |
| SCHEMBL4748159 | 0.78 | CNR1 (0.53) | PTGDR2PDPK1LOXL2GPR119CNR1 | |
| SCHEMBL28487238 | 0.71 | PDPK1 (0.52) | PTGDR2PDPK1LOXL2CYP1A1CYP1A2 | |
| SCHEMBL4671450 | 0.70 | LMNA (0.47) | CNR1 | |
| SCHEMBL5576871 | 0.70 | CNR1 (0.69) | CNR1 | |
| SCHEMBL468046 | 0.68 | PDPK1 (0.63) | PDPK1LOXL2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL4746902 | 0.68 | PHGDH (0.37) | CNR1HRH4 | |
| SCHEMBL4668903 | 0.68 | CNR1 (0.54) | CNR1 | |
| SCHEMBL30668080 | 0.65 | PDPK1 (0.60) | PTGDR2PDPK1LOXL2CYP1A1CYP1A2 | |
| SCHEMBL468088 | 0.65 | PDPK1 (0.60) | PTGDR2PDPK1LOXL2CYP1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008118141-A2 | USE OF CANNABINOID MODULATING COMPOUNDS IN COMBINATION WITH OTHER THERAPEUTIC COMPOUNDS FOR ADJUNCTIVE THERAPY | ACADIA PHARMACEUTICALS INC. (US) | 2008-10-02 | — | — | WO | disclosed |