Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 7/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | GSR | P00390 | 5/20 | 0.46 |
| ▸ | NGF | P01138 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747145 | 0.85 | GSR (0.55) | TDP2MEN1KMT2AGSRNGF | |
| SCHEMBL4748228 | 0.85 | TDP2 (0.49) | TDP2MEN1KMT2AUSP2GSR | |
| SCHEMBL5047468 | 0.84 | GSR (0.60) | TDP2MEN1KMT2AUSP2ALPL | |
| SCHEMBL4747662 | 0.82 | HRH4 (0.47) | TDP2MEN1KMT2AGSRNGF | |
| SCHEMBL4744197 | 0.82 | TDP2 (0.48) | TDP2MEN1KMT2AGSRNGF | |
| SCHEMBL4748217 | 0.80 | TDP2 (0.62) | TDP2MEN1KMT2AUSP2ALPL | |
| SCHEMBL4743788 | 0.74 | GSR (0.51) | GSRALOX5 | |
| SCHEMBL4747745 | 0.73 | MEN1 (0.48) | TDP2MEN1KMT2AUSP2ALPL | |
| SCHEMBL4748220 | 0.72 | GSR (0.48) | GSRALOX5 | |
| SCHEMBL4744200 | 0.70 | GSR (0.46) | GSRMAPTALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |
| WO-2008114009-A1 | 10H-BENZO(G)PTERDINE-2,4-DIONE COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISORDERS | CAMBRIDGE ENTERPRISE LTD. (GB) | 2008-09-25 | — | — | WO | disclosed |