Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | YTHDC1 | Q96MU7 | 5/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | PDE8A | O60658 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750901 | 0.87 | P2RX7 (0.41) | CYP11B1CYP11B2P2RX7YTHDC1PPARG | |
| SCHEMBL4751440 | 0.82 | CYP11B1 (0.47) | CYP11B1CYP11B2P2RX7CNR2HDAC6 | |
| SCHEMBL30332108 | 0.76 | YTHDC1 (0.60) | P2RX7YTHDC1PPARGPPARDLMNA | |
| SCHEMBL31238317 | 0.75 | P2RX7 (0.44) | P2RX7YTHDC1LMNATP53CNR2 | |
| SCHEMBL5161695 | 0.72 | YTHDC1 (0.70) | CYP11B2P2RX7YTHDC1PPARDLMNA | |
| SCHEMBL6268495 | 0.72 | PNP (0.53) | LMNA | |
| SCHEMBL29444616 | 0.71 | CDK1 (0.51) | P2RX7YTHDC1LMNATP53HDAC3 | |
| SCHEMBL183244 | 0.71 | CDK1 (0.51) | P2RX7YTHDC1LMNATP53HDAC3 | |
| SCHEMBL4751437 | 0.71 | CYP11B1 (0.47) | CYP11B1CYP11B2P2RX7CNR2 | |
| Hydrochloric Acid SCHEMBL17186583 | 0.71 | PNP (0.52) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | claimed |
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |