Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748530 | 0.87 | CYP11B1 (0.46) | P2RX7YTHDC1LMNATP53CYP11B1 | |
| SCHEMBL4752076 | 0.83 | FDPS (0.43) | P2RX7CYP11B1CYP11B2HDAC6 | |
| SCHEMBL30332411 | 0.73 | P2RX7 (0.49) | P2RX7YTHDC1LMNATP53HDAC3 | |
| SCHEMBL5158596 | 0.73 | P2RX7 (0.49) | P2RX7YTHDC1LMNATP53HDAC3 | |
| SCHEMBL11961126 | 0.73 | P2RX7 (0.52) | P2RX7YTHDC1LMNATP53HDAC3 | |
| SCHEMBL31237508 | 0.72 | P2RX7 (0.48) | P2RX7YTHDC1LMNATP53HDAC3 | |
| SCHEMBL8464465 | 0.71 | TK1 (0.51) | P2RX7YTHDC1LMNATP53HDAC3 | |
| SCHEMBL30332108 | 0.71 | YTHDC1 (0.60) | P2RX7YTHDC1LMNATP53CNR2 | |
| SCHEMBL944935 | 0.70 | P2RX7 (0.46) | P2RX7YTHDC1CNR2HDAC3HDAC4 | |
| SCHEMBL5161283 | 0.70 | HDAC1 (0.49) | P2RX7YTHDC1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | claimed |
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |