Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | BRAF | P15056 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788735 | 0.83 | PGR (0.32) | KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL14021476 | 0.81 | KDM4E (0.36) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL4895744 | 0.79 | PGR (0.32) | — | |
| SCHEMBL4820235 | 0.76 | PGR (0.39) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL4751237 | 0.75 | KDM4E (0.32) | KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL4608810 | 0.74 | PGR (0.34) | KDM4EMAPTKMT2AALDH1A1HSD17B10 | |
| SCHEMBL4789035 | 0.74 | KDM4E (0.38) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL4751693 | 0.73 | DHODH (0.39) | KDM4EMAPTKMT2AALDH1A1HPGD | |
| SCHEMBL4654589 | 0.72 | PGR (0.41) | KDM4EMAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL4814388 | 0.72 | KDM4E (0.40) | KDM4EMAPTKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |