Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14022483 | 0.82 | PGR (0.41) | KDM4EMEN1KMT2APGR | |
| SCHEMBL4788735 | 0.82 | PGR (0.32) | KDM4EMEN1MAPTTHRBKMT2A | |
| SCHEMBL4748730 | 0.81 | PGR (0.38) | KDM4EMEN1KMT2APGR | |
| SCHEMBL4654589 | 0.77 | PGR (0.41) | KDM4EMEN1MAPTKMT2APGR | |
| SCHEMBL4752246 | 0.77 | PGR (0.38) | KDM4EMEN1MAPTTHRBKMT2A | |
| SCHEMBL4608810 | 0.76 | PGR (0.34) | KDM4EMEN1MAPTKMT2APGR | |
| SCHEMBL4748740 | 0.75 | KDM4E (0.39) | KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4748819 | 0.74 | PGR (0.37) | KDM4EMEN1KMT2APGR | |
| SCHEMBL4895744 | 0.73 | PGR (0.32) | PGR | |
| SCHEMBL4904300 | 0.73 | PGR (0.34) | KDM4EMEN1KMT2APGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |