SCHEMBL4895744

SCHEMBL4895744

Cc1cc(Oc2c(C(C)C)nn(CS(C)(=O)=O)c2CO[PH](=O)O)cc(C)c1C#N

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4788735 0.87 PGR (0.32) PGR
SCHEMBL4888214 0.82 PGR (0.32) PGR
SCHEMBL4748740 0.79 KDM4E (0.39)
SCHEMBL14021468 0.76
SCHEMBL4654589 0.74 PGR (0.41) PGR
SCHEMBL4751237 0.73 KDM4E (0.32) PGR
SCHEMBL4884834 0.73 PGR (0.36) PGR
SCHEMBL4608810 0.72 PGR (0.34) PGR
SCHEMBL4748817 0.71 PGR (0.34) PGR
SCHEMBL4748819 0.70 PGR (0.37) PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008135824-A1 OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY PFIZER LIMITED (GB) 2008-11-13 WO disclosed