Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | RBP1 | P09455 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4748756 | 0.97 | MEN1 (0.47) | MEN1KMT2AHTTALDH1A1PHGDH | |
| SCHEMBL4744227 | 0.93 | MEN1 (0.42) | MEN1KMT2AHTTALDH1A1PHGDH | |
| SCHEMBL4744706 | 0.92 | CACNA1G (0.41) | MEN1KMT2AHTTALDH1A1CACNA1G | |
| SCHEMBL4747809 | 0.91 | CACNA1G (0.44) | MEN1KMT2AHTTALDH1A1CACNA1G | |
| SCHEMBL4744995 | 0.90 | MEN1 (0.41) | MEN1KMT2AHTTALDH1A1PHGDH | |
| SCHEMBL4744345 | 0.89 | CACNA1G (0.43) | MEN1KMT2AHTTALDH1A1CACNA1G | |
| SCHEMBL4748785 | 0.89 | CACNA1G (0.43) | MEN1KMT2AHTTALDH1A1CACNA1G | |
| SCHEMBL4744841 | 0.89 | MEN1 (0.39) | MEN1KMT2AHTTALDH1A1PHGDH | |
| SCHEMBL4744647 | 0.89 | KDM4E (0.40) | MEN1KMT2AHTTALDH1A1CACNA1G | |
| SCHEMBL4747027 | 0.89 | ALDH1A1 (0.40) | MEN1KMT2AHTTALDH1A1CACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008117148-A1 | SUBSTITUTED OXADIAZOLE ANALOGS AS CALCIUM CHANNEL ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2008-10-02 | — | — | WO | disclosed |