Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 5/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751578 | 0.96 | KDM4E (0.37) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4751257 | 0.83 | P2RY12 (0.37) | KDM4EALDH1A1KMT2AMEN1L3MBTL1 | |
| SCHEMBL4751664 | 0.80 | RAPGEF4 (0.33) | RAPGEF4 | |
| SCHEMBL4789035 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1LMNAKMT2AGLA | |
| SCHEMBL4752256 | 0.78 | AR (0.39) | ALOX15HPGDGPR119 | |
| SCHEMBL14022462 | 0.76 | ALDH1A1 (0.37) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL14021476 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4751035 | 0.76 | ALDH1A1 (0.39) | KDM4EALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL4751023 | 0.76 | KCNH2 (0.37) | LMNARAPGEF4 | |
| SCHEMBL4105032 | 0.75 | LRRK2 (0.37) | LMNAPOLBRAPGEF4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |