Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.39 |
| ▸ | PGR | P06401 | 3/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751257 | 0.90 | P2RY12 (0.37) | ARGPR119DHODHP2RY12HPGD | |
| SCHEMBL4751578 | 0.81 | KDM4E (0.37) | GPR119DHODHP2RY12HPGDALOX15 | |
| SCHEMBL4105299 | 0.78 | AR (0.41) | ARPGRHPGD | |
| SCHEMBL4751633 | 0.78 | AR (0.41) | ARPGRHPGD | |
| SCHEMBL4748837 | 0.78 | KDM4E (0.36) | GPR119HPGDALOX15 | |
| SCHEMBL4748870 | 0.77 | PGR (0.40) | ARPGRGPR119KDRCYP11B2 | |
| SCHEMBL4813064 | 0.74 | KDM4E (0.37) | ARPGRKDRCYP11B2MAP2K1 | |
| SCHEMBL1976965 | 0.72 | HSD17B10 (0.42) | DHODHHPGDALOX15 | |
| SCHEMBL4114557 | 0.71 | AR (0.37) | ARPGR | |
| SCHEMBL17479599 | 0.70 | CYP1A2 (0.44) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008135824-A1 | OXYALKYLPYRAZOLE COMPOUNDS USEFUL IN THERAPY | PFIZER LIMITED (GB) | 2008-11-13 | — | — | WO | disclosed |