Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT7 | O95251 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.40 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017801 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3KCNH2OPRK1 | |
| SCHEMBL2847273 | 0.77 | POLB (0.47) | — | |
| SCHEMBL4752711 | 0.76 | ALDH1A1 (0.50) | NPSR1 | |
| SCHEMBL5592323 | 0.76 | POLB (0.42) | — | |
| SCHEMBL4755192 | 0.75 | SLC6A2 (0.49) | KAT7SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL2850273 | 0.72 | KAT6A (0.49) | KAT7KAT6A | |
| SCHEMBL2850274 | 0.72 | KAT6A (0.49) | KAT7KAT6A | |
| SCHEMBL4972870 | 0.72 | ALDH1A1 (0.42) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL4776325 | 0.70 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3KCNH2CDK9 | |
| SCHEMBL2850980 | 0.69 | REN (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124582-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |