Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 7/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 5/20 | 0.46 |
| ▸ | PDE4A | P27815 | 4/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | TPMT | P51580 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3606707 | 0.91 | PDE4B (0.64) | PDE4BMEN1KMT2APTPN1PDE4D | |
| SCHEMBL5619093 | 0.86 | PDE4B (0.47) | PDE4BMEN1KMT2APTPN1NPC1 | |
| SCHEMBL10432719 | 0.84 | PDE4B (0.46) | PDE4BMEN1KMT2APTPN1NPC1 | |
| SCHEMBL7384113 | 0.81 | PDE4B (0.62) | PDE4BMEN1KMT2APDE4DPDE4A | |
| SCHEMBL11959784 | 0.80 | ABCG2 (0.63) | PDE4BMEN1KMT2APTPN1PDE4D | |
| SCHEMBL13311132 | 0.80 | MEN1 (0.49) | PDE4BMEN1KMT2APTPN1NPC1 | |
| SCHEMBL7235885 | 0.80 | ACHE (0.49) | PDE4BPTPN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7772633 | 0.80 | ACHE (0.49) | PDE4BPTPN1NPC1RAB9AALDH1A1 | |
| SCHEMBL3062913 | 0.79 | KMT2A (0.48) | PDE4BMEN1KMT2ANPC1RAB9A | |
| SCHEMBL2891959 | 0.79 | PDE4B (0.43) | PDE4BMEN1KMT2APTPN1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2963007-B1 | Synthesis of Calebin-A and its biologically active analogs | MAJEED MUHAMMED (US) | 2019-10-09 | — | — | EP | disclosed |
| US-9365486-B2 | Synthesis of calebin-A and its biologically active analogs | SAMI LABS LIMITED (IN) | 2016-06-14 | — | — | US | disclosed |
| US-20160002141-A1 | SYNTHESIS OF CALEBIN-A AND ITS BIOLOGICALLY ACTIVE ANALOGS | SAMI LABS LIMITED (IN) | 2016-01-07 | — | — | US | disclosed |
| EP-2963007-A1 | Synthesis of Calebin-A and its biologically active analogs | Majeed, Muhammed (US) | 2016-01-06 | — | — | EP | disclosed |
| WO-2008135886-A2 | QUINOLINE DERIVATIVES FOR USE IN THE INHIBITION OF THE GROWTH OF TUMOUR CELLS | UNIVERSITY OF PRETORIA (ZA) | 2008-11-13 | — | — | WO | disclosed |
| WO-2008135886-A2 | QUINOLINE DERIVATIVES FOR USE IN THE INHIBITION OF THE GROWTH OF TUMOUR CELLS | UNIVERSITY OF PRETORIA (ZA) | 2008-11-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160002141-A1 | SYNTHESIS OF CALEBIN-A AND ITS BIOLOGICALLY ACTIVE ANALOGS | CALD1, TFEB, CALU | PDE4B 2024/4885MEN1 2313/4885KMT2A 3616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.