Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.38 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235885 | 1.00 | ACHE (0.49) | ACHEPDE4BNPC1RAB9AALDH1A1 | |
| SCHEMBL7772772 | 0.85 | RAB9A (0.44) | PDE4BNPC1RAB9AALDH1A1SYK | |
| SCHEMBL818901 | 0.85 | RAB9A (0.44) | PDE4BNPC1RAB9AALDH1A1SYK | |
| SCHEMBL2891959 | 0.84 | PDE4B (0.43) | PDE4BALDH1A1PTPN1KDM4E | |
| SCHEMBL16397520 | 0.84 | SYK (0.47) | ACHEPDE4BRAB9AALDH1A1SYK | |
| SCHEMBL22320334 | 0.84 | PDE4B (0.40) | PDE4BNPC1RAB9AALDH1A1SYK | |
| SCHEMBL8962447 | 0.82 | PDE4B (0.44) | PDE4BNPC1RAB9AALDH1A1SYK | |
| SCHEMBL18362187 | 0.82 | ALDH1A1 (0.45) | PDE4BNPC1RAB9AALDH1A1SYK | |
| SCHEMBL723314 | 0.82 | PDE4B (0.39) | PDE4BNPC1RAB9AALDH1A1SYK | |
| SCHEMBL28630514 | 0.82 | PDE4B (0.39) | PDE4BNPC1RAB9AALDH1A1SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1119573-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000009512-A2 | BIPYRIDINE MANGANESE COMPLEXES | EUKARION, INC. (US) | 2000-02-24 | — | — | WO | disclosed |