Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 7/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | DDX3X | O00571 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.53 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA5A | P35218 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4746373 | 0.86 | ALOX5 (0.71) | TGM2MEN1KMT2AMAPTPOLB | |
| SCHEMBL19501282 | 0.82 | TGM2 (0.76) | TGM2MEN1KMT2AMAPTPOLB | |
| SCHEMBL5149342 | 0.81 | KMT2A (0.69) | TGM2MEN1KMT2AMAPTPOLB | |
| SCHEMBL19501652 | 0.81 | TGM2 (0.85) | TGM2KMT2AMAPTLMNAEGFR | |
| SCHEMBL14041475 | 0.80 | TGM2 (0.51) | TGM2MEN1KMT2AMAPTGAA | |
| SCHEMBL4746209 | 0.79 | MEN1 (0.60) | MEN1KMT2AMAPTPOLBDDX3X | |
| SCHEMBL6129390 | 0.78 | MEN1 (0.90) | MEN1KMT2AMAPTPOLBDDX3X | |
| SCHEMBL3919472 | 0.78 | TGM2 (1.00) | TGM2MEN1KMT2AMAPTPOLB | |
| Diphenylurea SCHEMBL27302793 | 0.77 | MEN1 (0.81) | MEN1KMT2AMAPTPOLBDDX3X | |
| SCHEMBL81209 | 0.77 | TGM2 (1.00) | TGM2LMNAEGFRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008122667-A2 | UREYLENE DERIVATIVES | SCHOOL OF PHARMACY (GB) | 2008-10-16 | — | — | WO | disclosed |