SCHEMBL5149342

SCHEMBL5149342

C=CC(=O)Nc1cccc([N+](=O)[O-])c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.69
MEN1 O00255 4/20 0.69
MAPT P10636 3/20 0.69
POLB P06746 3/20 0.69
DDX3X O00571 1/20 0.69
HTT P42858 1/20 0.69
CTDSP1 Q9GZU7 1/20 0.69
TGM2 P21980 2/20 0.67
SMN1; SMN2 Q16637 2/20 0.65
ALDH1A1 P00352 3/20 0.64
HSP90AA1 P07900 2/20 0.64
HPGD P15428 2/20 0.64
NPSR1 Q6W5P4 2/20 0.64
MAPK1 P28482 1/20 0.64
CACNA1B Q00975 1/20 0.64
APBA1 Q02410 1/20 0.64
NLRP1 Q9C000 1/20 0.64
BLM P54132 1/20 0.61
MAP2K7 O14733 1/20 0.60
NPC1 O15118 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14574133 0.86 TGM2 (0.59) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL27746161 0.85 KMT2A (0.66) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL31064998 0.85 KMT2A (0.56) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL6474687 0.82 KMT2A (0.75) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL6794151 0.82 MEN1 (0.73) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL6794156 0.82 MEN1 (0.73) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL1047211 0.82 MEN1 (1.00) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL4748934 0.81 TGM2 (0.62) KMT2AMEN1MAPTPOLBDDX3X
SCHEMBL4103284 0.81 TGM2 (0.76) TGM2MAP2K7
SCHEMBL1694713 0.80 KMT2A (0.77) KMT2AMEN1MAPTPOLBDDX3X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107915724-A Difficult to understand this of methanesulfonic acid replaces the preparation method of Buddhist nun 孙婷婷 2018-04-17 CN claimed
US-20260146122-A1 POLYMERS MOLECULAR MEDICAL LTD (GB) 2026-05-28 US disclosed
EP-4656249-A2 PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR Daewoong Pharmaceutical Co., Ltd. (KR) 2025-12-03 EP disclosed
EP-4594380-A1 POLYMERS Molecular Medical Ltd (GB) 2025-08-06 EP disclosed
US-20250136576-A1 Heterocyclic Compounds and Uses Thereof ACEA Therapeutics, Inc. (US) 2025-05-01 US disclosed
CN-118159533-A Heterocyclic compounds and their use 艾森医药有限公司 2024-06-07 CN disclosed
EP-4370212-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF ACEA Therapeutics, Inc. (US) 2024-05-22 EP disclosed
WO-2024069162-A1 POLYMERS MOLECULAR MEDICAL LTD (GB) 2024-04-04 WO disclosed
EP-3478687-B1 PYRAZOLOPYRIMIDINE DERIVATIVES AS KINASE INHIBITOR DAEWOONG PHARMACEUTICAL CO LTD (KR) 2024-03-20 EP disclosed
CN-115417827-B 6-amino-1, 3, 5-triazine compound and synthetic method and application thereof 中国药科大学 2023-05-26 CN disclosed
US-4985337-A ACID GENERATING AGENT AND COMPOUND DECOMPOSABLE WITH ACID KONICA CORPORATION (JP) 1991-01-15 US disclosed
EP-0207901-B1 ANTIANAPHYLACTIC AND ANTIBRONCHOSPASTIC N-BENZHYDRYLDIAZACYCLOALKYLALKANANILIDES RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1990-11-28 EP disclosed
EP-0369379-A2 Image forming method KONICA CORPORATION (JP) 1990-05-23 EP disclosed
EP-0362778-A2 Photosensitive composition Mitsubishi Chemical Corporation (JP) 1990-04-11 EP disclosed
EP-0345016-A2 Photosensitive composition and photosensitive lithographic printing plate KONICA CORPORATION (JP) 1989-12-06 EP disclosed
EP-0287212-A1 Positive photosensitive planographic printing plate Mitsubishi Chemical Corporation (JP) 1988-10-19 EP disclosed
US-4675319-A Antianaphylactic and antibronchospastic piperazinyl-(N-substituted phenyl)carboxamides, compositions and use RECORDATI S. A. CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1987-06-23 US disclosed
EP-0207901-A1 Antianaphylactic and antibronchospastic N-benzhydryldiazacycloalkylalkananilides RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1987-01-07 EP disclosed
US-4229514-A Photosensitive composition KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1980-10-21 US disclosed
US-4165365-A ANTIALLERGENS ESPECIALLY FOR ASTHMA SMITHKLINE CORPORATION (US) 1979-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146122-A1 POLYMERS FGB, IPMK, PFKP KMT2A 1376/4885MEN1 2614/4885MAPT 4398/4885
US-20250136576-A1 Heterocyclic Compounds and Uses Thereof CHEK2, CDK2, CDK1 KMT2A 2954/4885MEN1 1441/4885MAPT 3541/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.